BDBM50297471 1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)-4-methylindolin-2-one::CHEMBL557012

SMILES Cc1cccc2N(Cc3cc(F)cc4COCOc34)C(=O)C(N=O)c12

InChI Key InChIKey=JMGJSDSWOOEFNG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297471   

TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297471(1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3...)
Affinity DataKi:  700nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297471(1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3...)
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of ERK2 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed