BDBM50297477 4-ethyl-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)indolin-2-one::CHEMBL554060

SMILES CCc1cccc2N(Cc3cc(F)cc4COCOc34)C(=O)C(N=O)c12

InChI Key InChIKey=YNAKNLXNQMTXCI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297477   

TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297477(4-ethyl-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)m...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297477(4-ethyl-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)m...)
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of ERK2 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed