BDBM50298281 CHEMBL1091036::N-(4-Amino-2,6-diisopropylphenyl)-N'-{[1-[2-(3-hydroxypropoxy)phenyl]-4-(3-methoxyphenyl)piperidin-4-yl]-methyl}urea dihydrochloride

SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OCCCO

InChI Key InChIKey=HORIEIZZCKPONB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50298281   

TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50298281(CHEMBL1091036 | N-(4-Amino-2,6-diisopropylphenyl)-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed