BDBM50298898 2-hydroxy-N-(2-(3-methyl-2-oxo-7-(3-(trifluoromethyl)benzylamino)quinoxalin-1(2H)-yl)ethyl)acetamide::CHEMBL573829::CVT-12012

SMILES Cc1nc2ccc(NCc3cccc(c3)C(F)(F)F)cc2n(CCNC(=O)CO)c1=O

InChI Key InChIKey=HRAQDVZJYIAWOV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50298898   

TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50298898(2-hydroxy-N-(2-(3-methyl-2-oxo-7-(3-(trifluorometh...)
Affinity DataIC50:  38nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50298898(2-hydroxy-N-(2-(3-methyl-2-oxo-7-(3-(trifluorometh...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of stearoyl-CoA delta6 desaturase in rat microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50298898(2-hydroxy-N-(2-(3-methyl-2-oxo-7-(3-(trifluorometh...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of stearoyl-CoA delta5 desaturase in rat microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50298898(2-hydroxy-N-(2-(3-methyl-2-oxo-7-(3-(trifluorometh...)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed