BDBM50299000 (B)-(4R)-3-(2-Benzyl-3-(2-(2,6-dimethylphenoxy)acetamido)-2-hydroxypropanoyl)-N-((1S,2R)-2-hydroxy-1-indanyl)-5,5-dimethylthiazolidine-4-carboxamide::CHEMBL584192

SMILES Cc1cccc(C)c1OCC(=O)NC[C@](O)(Cc1ccccc1)C(=O)N1CSC(C)(C)[C@@H]1C(=O)N[C@@H]1[C@H](O)Cc2ccccc12

InChI Key InChIKey=PZCSYTKHAKPNOQ-RVFPNTRESA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50299000   

TargetPlasmepsin IV, putative(Plasmodium vivax)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50299000((B)-(4R)-3-(2-Benzyl-3-(2-(2,6-dimethylphenoxy)ace...)
Affinity DataKi:  120nMAssay Description:Inhibition of Plasmodium vivax plasmepsin 4 expressed in Escherichia coli BL21 (DE3) by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50299000((B)-(4R)-3-(2-Benzyl-3-(2-(2,6-dimethylphenoxy)ace...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 expressed in Escherichia coli BL21 (DE3) by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50299000((B)-(4R)-3-(2-Benzyl-3-(2-(2,6-dimethylphenoxy)ace...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed