BDBM50299048 2-(1,4'-bipiperidin-1'-yl)-6-(pyrimidin-5-yl)thiazolo[4,5-c]pyridine::CHEMBL575234

SMILES C1CCN(CC1)C1CCN(CC1)c1nc2cnc(cc2s1)-c1cncnc1

InChI Key InChIKey=UBBYLYDQJUESJK-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50299048   

TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299048(2-(1,4'-bipiperidin-1'-yl)-6-(pyrimidin-5-yl)thiaz...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299048(2-(1,4'-bipiperidin-1'-yl)-6-(pyrimidin-5-yl)thiaz...)
Affinity DataKi:  25nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50299048(2-(1,4'-bipiperidin-1'-yl)-6-(pyrimidin-5-yl)thiaz...)
Affinity DataIC50:  6.39E+3nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed