BDBM50299472 CHEMBL568300::Methyl 2-amino-4-methyl-5-phenylthiophene-3-carboxylate

SMILES COC(=O)c1c(N)sc(c1C)-c1ccccc1

InChI Key InChIKey=PXOVHWCIJDUPOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299472   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50299472(CHEMBL568300 | Methyl 2-amino-4-methyl-5-phenylthi...)
Affinity DataIC50:  3.00E+4nMAssay Description:Antagonist activity at human recombinant GluR5 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50299472(CHEMBL568300 | Methyl 2-amino-4-methyl-5-phenylthi...)
Affinity DataIC50:  4.10E+3nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed