BDBM50299822 (+/-)-syn-6,7-Bis(4-chlorophenyl)-12-methyl-7,12-dihydro-6Hchromeno[4,3-d][1,2,4]triazolo[1,5-a]pyrimidine::CHEMBL584299

SMILES CN1c2ncnn2C(C2=C1c1ccccc1OC2c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=TVZQVERUCXVELL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299822   

TargetCellular tumor antigen p53(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50299822((+/-)-syn-6,7-Bis(4-chlorophenyl)-12-methyl-7,12-d...)
Affinity DataIC50:  9.37E+3nMAssay Description:Induction of p53 in human HCT116 cells coexpressing pp53TA-luc assessed as inhibition of cell proliferation after 8 hrs by firefly/renilla luciferase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed