BDBM50300445 CHEMBL572545::N-hydroxy-10-methyl-9,10-dihydroacridine-9-carboxamide

SMILES CN1c2ccccc2C(C(=O)NO)c2ccccc12

InChI Key InChIKey=QZUGUUMWGJYJFD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300445   

TargetHistone deacetylase 5(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50300445(CHEMBL572545 | N-hydroxy-10-methyl-9,10-dihydroacr...)
Affinity DataIC50:  470nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC5 (620-1122) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50300445(CHEMBL572545 | N-hydroxy-10-methyl-9,10-dihydroacr...)
Affinity DataIC50:  1.91E+3nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC4 (612-1034) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50300445(CHEMBL572545 | N-hydroxy-10-methyl-9,10-dihydroacr...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC7 (438-915) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed