BDBM50300984 3-(2-(4-ethylpiperazin-1-yl)-2-oxoethylamino)-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[2,3-b]pyrazin-2(1H)-one::CHEMBL579669

SMILES CCCOCCn1c2cc(cnc2nc(NCC(=O)N2CCN(CC)CC2)c1=O)-c1ccc(OC)nc1

InChI Key InChIKey=SQZBWOCANVVLAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300984   

LigandPNGBDBM50300984(3-(2-(4-ethylpiperazin-1-yl)-2-oxoethylamino)-7-(6...)
Affinity DataIC50:  99nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50300984(3-(2-(4-ethylpiperazin-1-yl)-2-oxoethylamino)-7-(6...)
Affinity DataIC50:  0.380nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed