BDBM50302064 CHEMBL569946::N-(5-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-11-isobutyl-3,6,9,13-tetraoxo-5-(6-oxooctyl)-1,4,7,10-tetraazacyclotridecan-2-yl)pentyl)acetamide

SMILES CCC(=O)CCCCC[C@@H]1NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)C[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O

InChI Key InChIKey=LEWXBXMXEGUQKN-MKKRQWMVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50302064   

TargetHistone deacetylase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50302064(CHEMBL569946 | N-(5-((2S,5S,8S,11S)-8-((1H-indol-3...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50302064(CHEMBL569946 | N-(5-((2S,5S,8S,11S)-8-((1H-indol-3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50302064(CHEMBL569946 | N-(5-((2S,5S,8S,11S)-8-((1H-indol-3...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50302064(CHEMBL569946 | N-(5-((2S,5S,8S,11S)-8-((1H-indol-3...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human recombinant HDAC3 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed