BDBM50302212 (3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-2-yl)propylamino)methyl)-7,9-dihydro-2H-[1,4]dioxino[2,3-e]indol-8(3H)-one::(3S)-3-((3-(6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-2-yl)propylamino)methyl)-7,9-dihydro-2H-[1,4]dioxino[2,3-e]indol-8(3H)-one::CHEMBL566379

SMILES Fc1ccc2[nH]c3CC(CCCNC[C@H]4COc5c6CC(=O)Nc6ccc5O4)CCc3c2c1

InChI Key InChIKey=OTCAUALNGZOKLN-LWKPJOBUSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50302212   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302212((3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataKi:  6nMAssay Description:Agonist activity at 5-HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302212((3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302212((3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302212((3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302212((3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302212((3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataKi:  610nMAssay Description:Binding affinity to 5-HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302212((3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataKi:  610nMAssay Description:Binding affinity to 5-HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed