BDBM50302404 6-bromo-2-(2-chloro-6-fluorophenyl)-9-isopropyl-1H-phenanthro[9,10-d]imidazole::CHEMBL585110
SMILES CC(C)c1ccc2c3[nH]c(nc3c3ccc(Br)cc3c2c1)-c1c(F)cccc1Cl
InChI Key InChIKey=IFJAWEKHAKFJAP-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50302404
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mPGES1 in IL-1beta-stimulated human A549 cells assessed as blockade of PGH2 to PGE2 conversion in presence of 50% fetal bovine serumMore data for this Ligand-Target Pair