BDBM50302990 6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-(thiophen-2-ylmethyl)quinazolin-4-amine::CHEMBL566687

SMILES C(Nc1ncnc2ccc(cc12)-c1ccc2OCCOc2c1)c1cccs1

InChI Key InChIKey=GFOASKPCKCZBDL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302990   

TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302990(6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-(thiophe...)
Affinity DataIC50:  141nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302990(6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-(thiophe...)
Affinity DataIC50:  180nMAssay Description:Inhibition of Dyrk1A kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302990(6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-(thiophe...)
Affinity DataIC50:  126nMAssay Description:Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed