BDBM50302995 6-(furan-2-yl)-N-(thiophen-2-ylmethyl)quinazolin-4-amine::CHEMBL566062

SMILES C(Nc1ncnc2ccc(cc12)-c1ccco1)c1cccs1

InChI Key InChIKey=DQBNMNSFJFXDRV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302995   

TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302995(6-(furan-2-yl)-N-(thiophen-2-ylmethyl)quinazolin-4...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302995(6-(furan-2-yl)-N-(thiophen-2-ylmethyl)quinazolin-4...)
Affinity DataIC50:  3.48E+3nMAssay Description:Inhibition of Dyrk1A kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302995(6-(furan-2-yl)-N-(thiophen-2-ylmethyl)quinazolin-4...)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed