BDBM50307083 4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate::CHEMBL606201::US11753371, Compound JZL-195
SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3cccc(Oc4ccccc4)c3)CC2)cc1
InChI Key InChIKey=QNYRAEKLMNDRFY-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50307083
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of FAAH in mouse brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of MAGL in mouse brain membraneMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of ABHD6 in mouse brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 205nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant MAGL (unknown origin) expressed in COS7 cells assessed as blockade of substrate hydrolysis using AEA as substrate preincuba...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant MAGL incubated for 5 mins followed by substrate addition by cayman fluorescence based multimode microplate reader ass...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Bari Aldo Moro
Curated by ChEMBL
University Of Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant FAAH using AMC-AA as substrate preincubated with enzyme for 10 mins followed by substrate addition for 2 hrs by fluor...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Bari Aldo Moro
Curated by ChEMBL
University Of Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:FAAH inhibition assay was performed using Fatty Acid Amide Hydrolase Inhibitor Screening Assay Kit (Item #10005196), Cayman (1180 E Ellsworth Rd Ann ...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Bari Aldo Moro
Curated by ChEMBL
University Of Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant FAAH (unknown origin) expressed in COS7 cells assessed as blockade of substrate hydrolysis using 2-AG as substrate preincub...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Bari Aldo Moro
Curated by ChEMBL
University Of Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FAAH incubated for 5 mins followed by substrate addition by cayman fluorescence based multimode microplate reader ass...More data for this Ligand-Target Pair