BDBM50307768 7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide::CHEMBL598797::CUDC-101

SMILES COc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCCCCCC(=O)NO

InChI Key InChIKey=PLIVFNIUGLLCEK-UHFFFAOYSA-N

Data  34 IC50  1 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307768   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL

LigandBDBM50307768(7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)Copy SMILESCopy InChI

Affinity DataIC50:  2.40nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL

LigandBDBM50307768(7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)Copy SMILESCopy InChI

Affinity DataIC50:  16nMAssay Description:Inhibition of erbB2More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI