BDBM50307778 7-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ylthio)-N-hydroxyheptanamide::CHEMBL596754

SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1SCCCCCCC(=O)NO

InChI Key InChIKey=IXWWFHBAOSNFBD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307778   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307778(7-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquina...)
Affinity DataIC50:  2nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307778(7-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquina...)
Affinity DataIC50:  24nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed