BDBM50308245 CHEMBL590472::exo-6-[(Cyclobutyloxy)methyl]-6-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane

SMILES Clc1ccc(cc1Cl)[C@]1(COC2CCC2)[C@H]2CNC[C@@H]12

InChI Key InChIKey=IDZYJTXHWNKKBY-VIKVFOODSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50308245   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308245(CHEMBL590472 | exo-6-[(Cyclobutyloxy)methyl]-6-(3,...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308245(CHEMBL590472 | exo-6-[(Cyclobutyloxy)methyl]-6-(3,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2CD6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308245(CHEMBL590472 | exo-6-[(Cyclobutyloxy)methyl]-6-(3,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308245(CHEMBL590472 | exo-6-[(Cyclobutyloxy)methyl]-6-(3,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308245(CHEMBL590472 | exo-6-[(Cyclobutyloxy)methyl]-6-(3,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed