BDBM50308561 (+/-)-3-(4-((2R,3R)-3-hydroxybutan-2-yl)piperazin-1-yl)-1-(2-propoxyethyl)-7-(6-methoxypyridin-3-yl)pyrido[3,4-b]pyrazin-2(1H)-one::CHEMBL591942

SMILES CCCOCCn1c2cc(ncc2nc(N2CCN(CC2)[C@H](C)[C@@H](C)O)c1=O)-c1ccc(OC)nc1

InChI Key InChIKey=ZZHCAPMRVHYZMC-RTBURBONSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50308561   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50308561((+/-)-3-(4-((2R,3R)-3-hydroxybutan-2-yl)piperazin-...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human platelet PDE5 assessed as reduction in conversion of [3H]cGMP to [3H]GMP after 2 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed