BDBM50308562 (+/-)-3-(4-((2S,3R)-3-hydroxybutan-2-yl)piperazin-1-yl)-1-(2-isopropoxyethyl)-7-(6-methoxypyridin-3-yl)pyrido[3,4-b]pyrazin-2(1H)-one::CHEMBL589069
SMILES CCCOCCn1c2cc(ncc2nc(N2CCN(CC2)[C@@H](C)[C@@H](C)O)c1=O)-c1ccc(OC)nc1
InChI Key InChIKey=ZZHCAPMRVHYZMC-RBUKOAKNSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50308562
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of human ERG by patch-clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.330nMAssay Description:Inhibition of human platelet PDE5 assessed as reduction in conversion of [3H]cGMP to [3H]GMP after 2 hr by scintillation proximity assayMore data for this Ligand-Target Pair