BDBM50308780 1-(4-Hydroxymethylphenyl)-3-[4-(3-isopropyl-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl]urea::CHEMBL600258

SMILES CC(C)n1nnc2c(nc(nc12)-c1ccc(NC(=O)Nc2ccc(CO)cc2)cc1)N1CCOCC1

InChI Key InChIKey=KLBQEMTZKYSAER-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50308780   

LigandPNGBDBM50308780(1-(4-Hydroxymethylphenyl)-3-[4-(3-isopropyl-7-morp...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308780(1-(4-Hydroxymethylphenyl)-3-[4-(3-isopropyl-7-morp...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308780(1-(4-Hydroxymethylphenyl)-3-[4-(3-isopropyl-7-morp...)
Affinity DataIC50:  24.8nMAssay Description:Inhibition of human PI3Kgamma by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed