BDBM50310458 4-(1-cyclohexyl-1H-benzo[d]imidazol-2-yl)-1,2,5-oxadiazol-3-amine::CHEMBL1078929
SMILES Nc1nonc1-c1nc2ccccc2n1C1CCCCC1
InChI Key InChIKey=BCODCVMBVICQAV-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50310458
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:Inhibition of PKAalpha assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
Affinity DataKi: 720nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair