BDBM50311010 CHEMBL1078889::N-(4-{2-[4-(1,1-Dioxo-1lambda*6*-thiomorpholin-4-ylmethyl)-phenylamino]-pyrimidin-4-yl}-phenyl)-methanesulfonamide

SMILES CS(=O)(=O)Nc1ccc(cc1)-c1ccnc(Nc2ccc(CN3CCS(=O)(=O)CC3)cc2)n1

InChI Key InChIKey=NPIJYPKOHBKMAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311010   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311010(CHEMBL1078889 | N-(4-{2-[4-(1,1-Dioxo-1lambda*6*-t...)
Affinity DataIC50:  587nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311010(CHEMBL1078889 | N-(4-{2-[4-(1,1-Dioxo-1lambda*6*-t...)
Affinity DataIC50:  2nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed