BDBM50311650 (+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(7-fluorochroman-4-yl)-7H-purin-8(9H)-one::CHEMBL1080110

SMILES Fc1ccc2C(CCOc2c1)n1c2nc(ncc2[nH]c1=O)-n1cnc2ccccc12

InChI Key InChIKey=AWYBUVIAIMRQPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311650   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311650((+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(7-fluorochro...)
Affinity DataIC50:  95nMAssay Description:Inhibition of human JAK2 (532-1132) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311650((+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(7-fluorochro...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human JAK3 (508-1124) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed