BDBM50311762 1-(7-(2,6-dimethylbenzylamino)-1-(2-hydroxyethyl)-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridin-5-yl)pyridin-2(1H)-one::CHEMBL1080803

SMILES Cc1c(C)c2cc(nc(NCc3c(C)cccc3C)c2n1CCO)-n1ccccc1=O

InChI Key InChIKey=MONVGMXMCOSOEW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50311762   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311762(1-(7-(2,6-dimethylbenzylamino)-1-(2-hydroxyethyl)-...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of CYP3A4 using diethoxyfluorescein substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311762(1-(7-(2,6-dimethylbenzylamino)-1-(2-hydroxyethyl)-...)
Affinity DataIC50:  4.55E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311762(1-(7-(2,6-dimethylbenzylamino)-1-(2-hydroxyethyl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311762(1-(7-(2,6-dimethylbenzylamino)-1-(2-hydroxyethyl)-...)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311762(1-(7-(2,6-dimethylbenzylamino)-1-(2-hydroxyethyl)-...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed