BDBM50311799 (1R,5R)-3-(4-(3-(2-chloro-3,6-difluorophenoxy)propyl)phenyl)-N-cyclopropyl-N-(2,3-dichlorobenzyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxamide::CHEMBL1076449

SMILES Fc1ccc(F)c(OCCCc2ccc(cc2)C2=C([C@H]3CC[C@H](C2)N3)C(=O)N(Cc2cccc(Cl)c2Cl)C2CC2)c1Cl

InChI Key InChIKey=FUPYLBRXZJOVDD-SKCUWOTOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311799   

TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311799((1R,5R)-3-(4-(3-(2-chloro-3,6-difluorophenoxy)prop...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human rennin in human plasma assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311799((1R,5R)-3-(4-(3-(2-chloro-3,6-difluorophenoxy)prop...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311799((1R,5R)-3-(4-(3-(2-chloro-3,6-difluorophenoxy)prop...)
Affinity DataIC50:  0.550nMAssay Description:Inhibition of human rennin in buffer assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed