BDBM50312071 CHEMBL1080439::N-(3-(3-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)-4-chlorophenyl)-3-(trifluoromethyl)benzamide

SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1ccc(Cl)c(c1)-c1ccnc2c(cnn12)-c1cn[nH]c1

InChI Key InChIKey=RQGLQNLOJSOQJU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312071   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312071(CHEMBL1080439 | N-(3-(3-(1H-pyrazol-4-yl)pyrazolo[...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed