BDBM50312453 2-(4-(4,5-Bis(4-methoxyphenyl)thiazol-2-ylthio)-3-chlorophenyl)acetic Acid::CHEMBL1081044

SMILES COc1ccc(cc1)-c1nc(Sc2ccc(OCC(O)=O)cc2Cl)sc1-c1ccc(OC)cc1

InChI Key InChIKey=DUBAIPLHFTZYNK-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312453   

TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50312453(2-(4-(4,5-Bis(4-methoxyphenyl)thiazol-2-ylthio)-3-...)
Affinity DataEC50:  6.36E+3nMAssay Description:Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50312453(2-(4-(4,5-Bis(4-methoxyphenyl)thiazol-2-ylthio)-3-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50312453(2-(4-(4,5-Bis(4-methoxyphenyl)thiazol-2-ylthio)-3-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed