BDBM50312522 6-(((3S,4S)/(3R,4R)-4-(2-(2-(3-Fluorophenoxy)ethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine::CHEMBL1087746

SMILES Cc1cc(N)nc(CC2CNCC2OCCNCCOc2cccc(F)c2)c1

InChI Key InChIKey=OIQGPVIYDCPJQQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312522   

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50312522(6-(((3S,4S)/(3R,4R)-4-(2-(2-(3-Fluorophenoxy)ethyl...)
Affinity DataKi:  86nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli assessed as formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50312522(6-(((3S,4S)/(3R,4R)-4-(2-(2-(3-Fluorophenoxy)ethyl...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50312522(6-(((3S,4S)/(3R,4R)-4-(2-(2-(3-Fluorophenoxy)ethyl...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed