BDBM50314157 1-(1-(3-(3-(3-(2-hydroxyethylthio)-4-(trifluoromethyl)phenyl)-5-(methylsulfonyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)propyl)piperidin-4-yl)pyrrolidin-2-one::CHEMBL1093947

SMILES CS(=O)(=O)C1CCc2c(C1)c(nn2CCCN1CCC(CC1)N1CCCC1=O)-c1ccc(c(SCCO)c1)C(F)(F)F

InChI Key InChIKey=INJJZJNBIJVHGJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314157   

TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314157(1-(1-(3-(3-(3-(2-hydroxyethylthio)-4-(trifluoromet...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed