BDBM50314219 (R)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxy-2-(2'-(trifluoromethyl)biphenyl-4-ylsulfonamido)butanamide::CHEMBL1093689

SMILES ONC(=O)[C@@H](CCN1C(=O)c2ccccc2C1=O)NS(=O)(=O)c1ccc(cc1)-c1ccccc1C(F)(F)F

InChI Key InChIKey=HOKBADYASDUFAM-OAQYLSRUSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50314219   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50314219((R)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxy-2-(2'-(...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50314219((R)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxy-2-(2'-(...)
Affinity DataIC50:  430nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50314219((R)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxy-2-(2'-(...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of MMP1 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50314219((R)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxy-2-(2'-(...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of human recombinant ADAM17 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50314219((R)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxy-2-(2'-(...)
Affinity DataIC50:  390nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed