BDBM50314322 (Z)-1-(2-((4-(2-oxa-5-azabicyclo[2.2.2]octan-5-yl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methylene)-3-oxo-2,3-dihydrobenzofuran-5-yl)-3-(pyridin-3-yl)urea::CHEMBL1090709

SMILES Cn1cc(\C=C2/Oc3ccc(NC(=O)Nc4cccnc4)cc3C2=O)c2c(ccnc12)N1CC2CCC1CO2

InChI Key InChIKey=GGBNLUMJQIZYPI-GATIEOLUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314322   

LigandPNGBDBM50314322((Z)-1-(2-((4-(2-oxa-5-azabicyclo[2.2.2]octan-5-yl)...)
Affinity DataIC50:  249nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314322((Z)-1-(2-((4-(2-oxa-5-azabicyclo[2.2.2]octan-5-yl)...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed