BDBM50314353 (2Z)-4,6-dihydroxy-2-{[1-methyl-4-(4-methylpiperazin-1-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl]methylidene}-1-benzofuran-3(2H)-one::4,6-dihydroxy-2-((1-methyl-4-(4-methylpiperazin-1-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl)methylene)benzofuran-3(2H)-one::CHEMBL1094017

SMILES CN1CCN(CC1)c1ccnc2n(C)cc(\C=C3/Oc4cc(O)cc(O)c4C3=O)c12

InChI Key InChIKey=RLZIWQDVHJTWEF-NVMNQCDNSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314353   

LigandPNGBDBM50314353((2Z)-4,6-dihydroxy-2-{[1-methyl-4-(4-methylpiperaz...)
Affinity DataIC50:  43nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314353((2Z)-4,6-dihydroxy-2-{[1-methyl-4-(4-methylpiperaz...)
Affinity DataIC50:  0.940nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed