BDBM50315102 1-(4-(3-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-pyrazol-5-yl)piperidin-1-yl)ethanone::CHEMBL1092901

SMILES CC(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(F)cc1

InChI Key InChIKey=SKZVJZQVXSCUCD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315102   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50315102(1-(4-(3-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-pyraz...)
Affinity DataIC50:  82nMAssay Description:Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50315102(1-(4-(3-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-pyraz...)
Affinity DataIC50:  790nMAssay Description:Inhibition of human ERG by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50315102(1-(4-(3-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-pyraz...)
Affinity DataIC50:  1.68E+3nMAssay Description:Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed