BDBM50315516 CHEMBL1090455::N-(4-fluorophenylsulfonyl)-3-(1-(naphthalen-2-ylmethyl)-2,3-dioxoindolin-7-yl)acrylamide

SMILES Fc1ccc(cc1)S(=O)(=O)NC(=O)\C=C\c1cccc2C(=O)C(=O)N(Cc3ccc4ccccc4c3)c12

InChI Key InChIKey=DLVKVJKYUMOUBT-XNTDXEJSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315516   

TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315516(CHEMBL1090455 | N-(4-fluorophenylsulfonyl)-3-(1-(n...)
Affinity DataIC50:  33.9nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315516(CHEMBL1090455 | N-(4-fluorophenylsulfonyl)-3-(1-(n...)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed