BDBM50315652 CHEMBL1090143::N-(3-(6-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-yl)phenyl)-3-(trifluoromethyl)benzamide

SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1cccc(c1)-c1ncnc2sc(cc12)-c1ccncc1

InChI Key InChIKey=CXIYVOOQCNGGIB-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50315652   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50:  80nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IKK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ITKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LYNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed