BDBM50316514 (2R)-N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridine-4-yl]-2-hydroxypropanamide::(2S)-N-(6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-4-yl)-2-hydroxypropanamide::CHEMBL1094521

SMILES C[C@H](O)C(=O)NC1CC(C)(C)Oc2nc(-c3ccc(Cl)cc3Cl)c(cc12)-c1ccc(Cl)cc1

InChI Key InChIKey=XCFWDLWOCXSJOK-JRTLGTJJSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50316514   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316514((2R)-N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]CP55940 from human recombinant cannabinoid CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316514((2R)-N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-...)
Affinity DataIC50:  4.80E+3nMAssay Description:Displacement of [3H]CP55940 from human recombinant cannabinoid CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316514((2R)-N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-...)
Affinity DataIC50:  120nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316514((2R)-N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of cannabinoid CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316514((2R)-N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316514((2R)-N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-...)
Affinity DataIC50:  4.80nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316514((2R)-N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-...)
Affinity DataIC50:  2.26E+3nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316514((2R)-N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-...)
Affinity DataIC50:  4.80nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316514((2R)-N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-...)
Affinity DataIC50:  2.26E+3nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316514((2R)-N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-...)
Affinity DataIC50:  2.26E+3nMAssay Description:Inhibition of cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed