BDBM50316540 CHEMBL1098763::N,N'-(Propane-1,3-diyl)bis(8-hydroxy-2-imino-2H-chromene-3-carboxamide)

SMILES Oc1cccc2cc(C(=O)NCCCNC(=O)c3cc4cccc(O)c4oc3=N)c(=N)oc12

InChI Key InChIKey=NKEWQXUSKCGFTE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316540   

TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316540(CHEMBL1098763 | N,N'-(Propane-1,3-diyl)bis(8-hydro...)
Affinity DataIC50:  4.82E+4nMAssay Description:Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316540(CHEMBL1098763 | N,N'-(Propane-1,3-diyl)bis(8-hydro...)
Affinity DataIC50:  3.48E+4nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed