BDBM50316541 CHEMBL1096801::N,N'-(Propane-1,3-diyl)bis(7-hydroxy-2-imino-2H-chromene-3-carboxamide)

SMILES Oc1ccc2cc(C(=O)NCCCNC(=O)c3cc4ccc(O)cc4oc3=N)c(=N)oc2c1

InChI Key InChIKey=VLAVPACPOLPQDN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316541   

TargetDynamin-1(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316541(CHEMBL1096801 | N,N'-(Propane-1,3-diyl)bis(7-hydro...)
Affinity DataIC50:  6.61E+4nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316541(CHEMBL1096801 | N,N'-(Propane-1,3-diyl)bis(7-hydro...)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed