BDBM50316542 CHEMBL1098764::N,N'-(Propane-1,3-diyl)bis(7,8-dihydroxy-2-imino-2H-chromene-3-carboxamide)

SMILES Oc1ccc2cc(C(=O)NCCCNC(=O)c3cc4ccc(O)c(O)c4oc3=N)c(=N)oc2c1O

InChI Key InChIKey=WOZKPVAKLXHYED-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50316542   

TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316542(CHEMBL1098764 | N,N'-(Propane-1,3-diyl)bis(7,8-dih...)
Affinity DataIC50:  390nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316542(CHEMBL1098764 | N,N'-(Propane-1,3-diyl)bis(7,8-dih...)
Affinity DataIC50:  9.95E+4nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316542(CHEMBL1098764 | N,N'-(Propane-1,3-diyl)bis(7,8-dih...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed