BDBM50316788 4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hexahydro-1H-carbazol-6-yloxy)ethyl)phenol hydrochloride::CHEMBL1098120

SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1

InChI Key InChIKey=PGZRUXOTUOXUCU-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50316788   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  1.22E+3nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 250 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  1.00E+3nMAssay Description:Noncompetitive inhibition of EGFR after 30 mins by chemiluminescence ELISA in presence of 250 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  2.19E+3nMAssay Description:Noncompetitive inhibition of VEGFR3 after 30 mins by chemiluminescence ELISA in presence of 250 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  1.01E+3nMAssay Description:Noncompetitive inhibition of EGFR after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  2.17E+3nMAssay Description:Noncompetitive inhibition of VEGFR3 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  1.09E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  1.04E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 250 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  2.11E+3nMAssay Description:Noncompetitive inhibition of VEGFR3 after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of VEGFR2 after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  980nMAssay Description:Noncompetitive inhibition of EGFR after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  2.17E+3nMAssay Description:Inhibition of VEGFR3 after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of EGFR after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  930nMAssay Description:Inhibition of IGF1R after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  930nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  1.06E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316788(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)
Affinity DataIC50:  990nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed