BDBM50316921 (S)-1-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)-N,N-dimethylpyrrolidin-3-amine::CHEMBL1087493

SMILES CCOCCn1c(nc2ccccc12)N1CC[C@@H](C1)N(C)C

InChI Key InChIKey=VILNAIPEYFWQQH-AWEZNQCLSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50316921   

TargetHistamine H1 receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50316921((S)-1-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)...)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50316921((S)-1-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)...)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]N-methyl scopolamine from human muscarinic M1 receptor expressed in CHO Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50316921((S)-1-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50316921((S)-1-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)...)
Affinity DataIC50:  233nMAssay Description:Inhibition of human ERG channel by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50316921((S)-1-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed