BDBM50318030 ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyltriphosphate tetraammonium salt::CHEMBL1094109
SMILES CNc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O
InChI Key InChIKey=LCQWKKZWHQFOAH-IOSLPCCCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50318030
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University Of Pavia
Curated by ChEMBL
University Of Pavia
Curated by ChEMBL
Affinity DataIC50: 112nMAssay Description:Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X7R expressed in HEK293 cells assessed as reduction in YO-PRO-1 iodide dye uptake preincubated for 30 mins followed by YO...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 263nMAssay Description:Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X4R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X7R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 1.29E+3nMAssay Description:Agonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair