BDBM50318159 8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-ylamino)-ethyl]-1H-quinolin-2-one::CHEMBL1095777::INDACATEROL

SMILES CCc1cc2CC(Cc2cc1CC)NC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12

InChI Key InChIKey=QZZUEBNBZAPZLX-QFIPXVFZSA-N

Data  10 KI  6 IC50  13 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318159   

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theravance Biopharma

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressing CHO-K1 cells incubated for 60 mins or 6 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Theravance Biopharma

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)
Affinity DataEC50:  0.794nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as cAMP accumulation using [125I]cAMP by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank