BDBM50318653 3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno[2,3-b]pyridine-2-carboxamide::3-amino-N-(3-fluorophenyl)-6-thiophen-2-ylthieno[2,3-b]pyridine-2-carboxamide::CHEMBL1084955::NadD inhibitor 3_02::US8785499, 3_02

SMILES Nc1c(sc2nc(ccc12)-c1cccs1)C(=O)Nc1cccc(F)c1

InChI Key InChIKey=UCTSEHMMSSIODN-UHFFFAOYSA-N

Data  6 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318653   

TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
University Of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50318653(3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of NaMN substrate by malachite gre...More data for this Ligand-Target Pair
TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
University Of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50318653(3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno...)
Affinity DataKi:  3.20E+4nMAssay Description:Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of ATP substrate by malachite gree...More data for this Ligand-Target Pair