BDBM50319557 (R)-5-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinolin-2-yl)thiophene-2-carbonitrile::CHEMBL1086315
SMILES C[C@@H]1CCCN1CCc1ccc2nc(ccc2c1)-c1ccc(s1)C#N
InChI Key InChIKey=MHAQFNSWCQLYOT-OAHLLOKOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50319557
Affinity DataKi: 0.300nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from rat cloned histamine H3 receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 480nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG by Competitive binding assayMore data for this Ligand-Target Pair