BDBM50320101 CHEMBL1082621::N-(2-(dimethylamino)ethyl)-4-(3-(2-((7-fluoro-5-methoxy-2-(1,3,5-trimethyl-1H-pyrazol-4-yl)-1H-indol-3-yl)methylene)-3-oxo-2,3-dihydrobenzofuran-5-yl)ureido)-N-methylbenzamide

SMILES COc1cc(F)c2[nH]c(c(\C=C3\Oc4ccc(NC(=O)Nc5ccc(cc5)C(=O)N(C)CCN(C)C)cc4C3=O)c2c1)-c1c(C)nn(C)c1C

InChI Key InChIKey=YKPMNBJYASHWAN-ZCTHSVRISA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50320101   

LigandPNGBDBM50320101(CHEMBL1082621 | N-(2-(dimethylamino)ethyl)-4-(3-(2...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50320101(CHEMBL1082621 | N-(2-(dimethylamino)ethyl)-4-(3-(2...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50320101(CHEMBL1082621 | N-(2-(dimethylamino)ethyl)-4-(3-(2...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of PI3deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50320101(CHEMBL1082621 | N-(2-(dimethylamino)ethyl)-4-(3-(2...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of PI3gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50320101(CHEMBL1082621 | N-(2-(dimethylamino)ethyl)-4-(3-(2...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed