BDBM50320891 9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromide::CHEMBL1164137

SMILES COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OCCCOc1ccc(Cl)cc1

InChI Key InChIKey=JJPOWRAZNKDAPG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50320891   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50320891(9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromid...)
Affinity DataIC50:  715nMAssay Description:Inhibition of electric eel AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Staphylococcus aureus)TBA
LigandPNGBDBM50320891(9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromid...)
Affinity DataIC50:  3.78E+4nMAssay Description:Inhibition of Staphylococcus aureus recombinant FTsZ preincubated for 10 mins followed by compound addition measured after 30 mins by Cytophos phosph...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)TBA
LigandPNGBDBM50320891(9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromid...)
Affinity DataIC50:  7.74E+4nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged FtsZ GTPase activity expressed in Escherichia coli BL21(DE3) preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50320891(9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromid...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed