BDBM50321197 CHEMBL1163480::rac-3-(4-Nitrophenylamino)-1-(4-chlorophenyl)-3-cyclohexylpropan-1-one

SMILES [O-][N+](=O)c1ccc(NC(CC(=O)c2ccc(Cl)cc2)C2CCCCC2)cc1

InChI Key InChIKey=WHDYNTOHHUJBCQ-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50321197   

TargetProgesterone receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321197(CHEMBL1163480 | rac-3-(4-Nitrophenylamino)-1-(4-ch...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]progesterone from human progesterone receptor B after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321197(CHEMBL1163480 | rac-3-(4-Nitrophenylamino)-1-(4-ch...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]DHT from human androgen receptor after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321197(CHEMBL1163480 | rac-3-(4-Nitrophenylamino)-1-(4-ch...)
Affinity DataIC50:  216nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321197(CHEMBL1163480 | rac-3-(4-Nitrophenylamino)-1-(4-ch...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed